Decoding the Clinical Spectrum of Semisynthetic Cannabinoid Toxicity
Date and Time:
Tuesday, February 4th, 8:00 PM EST
Location – Virtual Meeting
https://us02web.zoom.us/j/83722922366?pwd=QjZ3V0xNWHZ0OVZ0b3BpbWd3STRqUT09\
Event Description:
This journal club will explore the rising public health concern of semisynthetic cannabinoids (SSCs), focusing on their toxicity and the increasing reports of associated adverse events. SSCs, such as hexahydrocannabinol (HHC), are often marketed as legal alternatives to traditional cannabis, but they can have potent and unpredictable effects. The discussion will center on thew case reports by Puri (2024) and Reiter (2024) which describes patients who developed potentially life-threatening symptoms after using synthetic or semi-synthetic cannabinoids. Key discussion points will include the challenges of regulating these substances, the lack of understanding regarding their long-term effects, and the need for greater awareness among clinicians and policymakers.
Featured Articles:
Puri, A., Costanzo, F., Rivera, J. & Bujdos, J. Catatonia Induced by First-Time Use of Synthetic Cannabinoids: A Case Report. Cureus 16, e53324 (2024).
Reiter, N. et al. Severe poisoning with semi-synthetic cannabinoids. Ugeskr. Læg. 186, 1–5 (2024).
O’Mahony, B., O’Malley, A., Kerrigan, O. & McDonald, C. HHC-induced psychosis: a case series of psychotic illness triggered by a widely available semisynthetic cannabinoid. Ir. J. Psychol. Med. 1–4 (2024) doi:10.1017/ipm.2024.3.
Speakers:
Phil Molloy, MD – Clinical education expert
Teresa Simon, MPH – Public health epidemiologist
Jahan Marcu, PhD – Cannabis researcher
Questions? Email Prctrials.info@gmail.com
PRC+ has education modules available for health care professionals: https://www.prc-trials-plus.com/education